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US: Scientist II in Biotech

Date: 01-Oct-2015
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Scientist II, Chem & Mol Therapeutics

The successful candidate will work in a small team to develop approaches to generate and validate target hypotheses for candidate therapeutics emerging from functional genomic or chemoproteomic screens.

He/she will support target identification and validation efforts through developing cellular, molecular, and chemical biology tools to identify and characterize small molecule - protein interactions and regulation of signaling pathways. He/she will closely collaborate with our mass spectrometry (proteomics) and phenotypic screening programs. Active interfacing with therapeutic research teams - in neurology, immunology, tissue repair, and hematology areas - and participating in project teams will also be essential responsibilities.

Qualifications Molecular and cellular biology skills in cloning, transfections, RNAi methodologies and familiarity with cell-based assays are required.

The candidate is also required to have a solid understanding of signaling pathways. Experience with genome editing techniques (e.g. CRISPR/Cas9, ZFN, TALEN) , RNAseq, basic small molecule pharmacology, target identification, mechanism of action, chemoproteomics, and chemical biology approaches is a plus.

Strong record of delivering biological insights through chemical, molecular, and cellular studies is highly desirable.

Education PhD in cell biology, molecular biology, or chemical biology

To apply for this position, please visit this Website.

Thank you,
BioTech FYI Center