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US-MA-Cambridge: Senior Scientist, Biochemistry

Date: 05-Nov-2013
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Senior Scientist, Biochemistry

Looking for a senior scientist who is passionate about exploring the potential for leveraging epigenetics to create life-changing therapies for patients with neurodegenerative, inflammatory, hematologic and fibrotic diseases.

• Extensive experience with isolation of biomolecules, including protein-protein and protein-nucleic acid complexes, and protein purification • Proven experience with mammalian, fungal and bacterial cell growth for production and isolation of proteins and nucleic acids • Knowledge of affinity purification techniques for isolation of biomolecules • Experience with isolation of nucleic acids in support of transcriptomic, genomic and epigenomic analyses • Experience with biochemical assay development to understand protein activity, and protein-protein and protein-nucleic acid interaction • Background in physical biochemistry including catalytic mechanisms, binding kinetics and affinity, molecular docking • Experience withInterest in methods development, e.g., affinity capture, protein-protein interaction, protein-nucleic acid interaction preferred • Familiarity with chemical, biochemical and biological data • Willingness to engage and ability to coordinate multiple collaborative projects within a cross-functional team environment • Highly self-motivated, with excellent organizational, and oral and written communication skills • Experience in training, mentoring and managing junior colleagues • Experience with LIMS a plus • Relevant publications in peer-reviewed journals expected in support of candidacy • Demonstrates independent scientific thinking, and solves complex technical and scientific problems with significant impact on major drug discovery and development projects

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Thank you,
BioTech FYI Center
http://biotech.fyicenter.com/