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US-MA-Cambridge: Scientist Translational Research

Date: 26-Apr-2011
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Scientist Translational Research in Biotech

* Target evaluation for novel, clinically-relevant, oncology targets * Development and use of relevant in vivo models including subcutaneous, orthotopic, hematological and metastatic tumor models * Establishment of target-based pharmaco-dynamic assays * Proficiency with compound formulation, tumor efficacy and PK/PD assays for single treatment or in combinations. * Development of tumor and serum biomarkers using pharmacogenomic approaches. * Interacting with multidisciplinary teams of scientists internally * Internal and external presentations in scientific conferences * Supervision of Research Associates

* PhD in molecular biology, pharmacology, cancer genetics or equivalent * 3+ yrs of working biotech/ pharmaceutical/ or academia experience * Working knowledge of major cancer pathways and associated assays * Experience with angiogenesis, hypoxia, mechanisms of drug resistance, tumor microenvironment, metastasis, cancer stem cells desirable * Familiarity with molecular profiling and cancer genomics * Record of scientific excellence through high-quality publications and presentations * Proven ability to work effectively in a team setting, excellent communication skills * People management experience

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