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US-MA-Waltham: Staff Scientist in Biotech

Date: 22-Feb-2011
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Staff Scientist - Protein Chemistry

KEY DUTIES: Lead characterization efforts for candidate lead proteins; development and execution of analytical and biochemical assays. Plan comprehensive studies; manage, analyze, and interpret data Research and recommend purchase of capital equipment as appropriate and required. Interface with external resources to augment internal capabilities Adapt new technologies and identify proprietary opportunities


Laboratory experience in protein expression, purification, and biochemistry and biophysics techniques, including, but not limited to SDS-PAGE, Western Blotting, ELISA, in vitro activity assays, glycoform analysis, LC-MS, ITC, FRET, FP, SPR, NMR, equilibrium dialysis, protein ultracentrifugation. In depth understanding of enzyme kinetics and protein thermodynamics. Experience with protein structure-function, molecular modeling, and protein engineering. Strong understanding of experimental design principles and statistics Experience supporting protein therapeutic discovery in an industrial setting Familiarity with protein therapeutic drug development (formulation, manufacturing, clinical)

PERSONAL SKILLS: Committed to maintaining high standards in quality of science Strong sense of urgency; ability to work at a fast pace under aggressive timelines Proactive, Motivated, adaptable self starter; able to muti-task Strong collaborator, ability to work in a team setting Critical, analytical thinker Strong communication and organizational skills

MINIMUM EDUCATION AND EXPERIENCE PhD in a relevant scientific discipline (chemistry, biochemistry, biophysics) with 6+ years of experience in the pharmaceutical/biotechnology industry

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