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Bioinformatics Glossary
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Karyotype
The constitution (typically number and size) of chromosomes in a cell
or individual.
Knockout mice (gene targeting)
Mice which have been engineered to lack a chosen gene. The gene is inactivated
in so called embryonic stem cells using the technique of homologous recombination.
These cells are then introduced into a early stage embryo (blastocyst)
and this is then transplanted into a recipient mouse. The subsequent progeny
lack the targeted gene in some cells. This technique is used to determine
the function of the chosen gene.
(Continued on next part...)
Part:
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
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