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Bioinformatics Glossary
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Weight matrix
The density of binding sites in a gene or sequence can be used to derive
a ratio of density for each element in a pattern of interest. The combined
individual density ratios of all elements are then collectively used to
build a scoring profile known as a weight matrix. This profile can be used
to test the prediction of the identification of the selected pattern and
the ability of the algorithm to discriminate them from non-pattern sequences.
Western blot
Technique in which specific antibodies are used to identify their antigens
from a mixture of proteins. Typically, these proteins mixtures are first
separated by electrophoresis and then transfered onto nylon sheets by electrotransfer.
Radiolabeled or enzyme-linked antibodies are incubated with the sheets
and unbound antibodies washed away allowing the position of the bound antibody
to be revealed by autoradiography or color which is formed upon addition
of a substrate.
Wild type
Form of a gene or allele that is considered the "standard" or most common.
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Part:
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
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