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Bioinformatics Glossary
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(Continued from previous part...)
Bacterial artificial chromosome (BAC): Cloning
vector that can incorporate large fragments of DNA. (see YACS)
Bacteriophage: A virus that infects bacteria.
The bacteriophage DNA has served as a basis for cloning vectors, and is
also utilized to create phage libraries containing human or other genes.
Baculovirus: An insect virus which forms the
basis of a protein expression system
Base pair: A pair of nitrogenous bases (a purine
and a pyrimidine), held together by hydrogen bonds, that form the core
of DNA and RNA i.e the A:T, G:C and A:U interactions.
Beta sheet: A three dimensional arrangement
taken up by polypeptide chains that consists of alternating strands linked
by hydrogen bonds. The alternating strands together form a sheet that is
frequently twisted. One of the secondary structural elements characteristic
of proteins.
Bioinformatics:
1.The field of endeavor that relates to the collection, organization
and analysis of large amounts of biological data using networks of computers
and databases (usually with reference to the genome project and DNA sequence
information).
2. Bioinformatics, sometimes, is used interchangeably with the term
Computational
Biology. Precisely, Computational Biology is defined as the systematic
development and application of computing systems and computational solution
techniques to models of biological phenomena; Bioinformatics is defined
as the systematic development and application of computing systems and
computational solution techniques analyzing data obtained by experiments,
modeling, database search, and instrumentation regarding biological aspect.
Bivalent: Having two binding sites; having
2 free electrons available for binding.
Blunt-end (ligation): The joining of DNA fragments
that contain no overhang at either end and consequently no DNA bases available
for hybridization (cf. sticky-end ligation).
(Continued on next part...)
Part:
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
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